By driving
Syracuse Hancock International Airport can be accessed directly off of Interstate 81 (north–south), which is connected to Interstate 90 and the New York State Thruway. There are both parking facilities and car rental services at the airport.
By taxi
Like most of New York, taxis can be flagged down in the street. However, you might want to pre-order a taxi if for convenience and peace of mind. This can be done by done at the person(s) in charge of your accommodation, for example, at the front desk of a hotel.
By bus
The public bus system in Syracuse, Centro, doesn't stop at Syracuse International Airport. The closest bus station that Centro travels to is William F. Walsh Regional Transportation Center, which is a few miles away from the airport. There are many taxis situated outside of William F. Walsh Regional Transportation Center that will drive you to the airport.